Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway

Abstract Globally, uveitis is a collection of intraocular inflammatory disorders that affect mainly the uvea, resulting in irreversible blindness and a heavy socioeconomic burden.Excessive autoimmune inflammation and oxidative stress are major drivers that contribute to the initiation and progression of uveitis.Nevertheless, current therapeutic met

read more


Impact of Waddlia chondrophila infection on pregnancy in the mouse

The intracellular bacterium Waddlia chondrophila, which belongs to the Chlamydiales order, was found to be associated with miscarriage in humans.There is little to no knowledge regarding the mode of infection, impact on the neonate and pathophysiology of this emerging bacterium.We have previously shown that W.chondrophila induces a systemic infecti

read more


On the Performance Analysis of Decode-and-Forward Multi-Hop Hybrid FSO/RF Systems With Hard-Switching Configuration

In this paper, we introduce a decode-and-forward multi-hop hybrid free-space optical/radio frequency (FSO/RF) system.The FSO link is assumed to follow Gamma-Gamma distribution with the combined effects of pointing errors and path loss under intensity modulation with direct detection technique, and the RF link Raglan Shirt is assumed to follow Nakag

read more